7-Methylxanthine

7-Methylxanthine
Clinical data
Other names	7-MX; 7-Methylxanthin; Heteroxanthin; Heteroxanthine; NSC-7861
Identifiers
	IUPAC name 7-methyl-3H-purine-2,6-dione;
CAS Number	552-62-5;
PubChem CID	68374;
ChemSpider	61660;
UNII	E9M81NJM6G;
KEGG	C16353;
ChEBI	CHEBI:48991;
ChEMBL	ChEMBL321248;
Chemical and physical data
Formula	C6H6N4O2
Molar mass	166.140 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CN1C=NC2=C1C(=O)NC(=O)N2;
	InChI InChI=1S/C6H6N4O2/c1-10-2-7-4-3(10)5(11)9-6(12)8-4/h2H,1H3,(H2,8,9,11,12); Key:PFWLFWPASULGAN-UHFFFAOYSA-N;

7-Methylxanthine (7-MX), also known as heteroxanthine, is an active metabolite of caffeine (1,3,7-trimethylxanthine) and theobromine (3,7-dimethylxanthine).^[1]^[2] It is a non-selective antagonist of the adenosine receptors.^[1]^[2] The compound may slow the progression of myopia (nearsightedness).^[1]^[2] It is under investigation for this purpose in children with myopia.^[1]^[2]

References

1 2 3 4 "7-Methylxanthine". Inxight Drugs. Retrieved 24 August 2022.
1 2 3 4 Singh H, Singh H, Latief U, Tung GK, Shahtaghi NR, Sahajpal NS, et al. (August 2022). "Myopia, its prevalence, current therapeutic strategy and recent developments: A Review". Indian Journal of Ophthalmology. 70 (8): 2788–2799. doi:10.4103/ijo.IJO_2415_21. PMID 35918918. S2CID 251281523.

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[InxightDrugs-1] 1 2 3 4 "7-Methylxanthine". Inxight Drugs. Retrieved 24 August 2022.

[pmid35918918-2] 1 2 3 4 Singh H, Singh H, Latief U, Tung GK, Shahtaghi NR, Sahajpal NS, et al. (August 2022). "Myopia, its prevalence, current therapeutic strategy and recent developments: A Review". Indian Journal of Ophthalmology. 70 (8): 2788–2799. doi:10.4103/ijo.IJO_2415_21. PMID 35918918. S2CID 251281523.

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