Angiolipoma

Angiolipoma
Other names: Other specified lipoma[1]
Angiolipoma foot
SymptomsMultiple tender lumps just under the skin[1]
Usual onsetSecond/third decade of life[1]
CausesUnknown[1]
PrognosisGood, typically do not recur[1]
FrequencyCommon[1]

Angiolipoma is a non-cancerous soft tissue tumor.[1] It generally presents as multiple tender lumps just under the skin, most frequently affecting the limbs and less commonly the trunk.[1]

The cause is unknown.[1] It has all other features of a typical lipoma.[2]: 624 [3] When surgically removed, it appears yellow-red with a capsule.[1] Under the microscope, it features mature adipocytes and branching vessels of capillary size, which typically contain fibrin thrombi.[1]

Males are affected more frequently than females.[1] Around 5% of cases run in families in an autosomal dominant manner.[1]

Signs and symptoms

  • Large mediastinal angiolipoma
    Large mediastinal angiolipoma

Pathology

  • Small vessels in adipose tissue
    Small vessels in adipose tissue
  • Small vessels in adipose tissue
    Small vessels in adipose tissue
  • Small vessels in adipose tissue
    Small vessels in adipose tissue
  • Small vessels in adipose tissue
    Small vessels in adipose tissue
  • The vessels typically contain hyaline or fibrin (pictured) thrombi
    The vessels typically contain hyaline or fibrin (pictured) thrombi[4]

Diagnosis

It may appear similar to Kaposi sarcoma and angiosarcoma.[1]

Treatment

See also

References

  1. 1 2 3 4 5 6 7 8 9 10 11 12 13 14 WHO Classification of Tumours Editorial Board, ed. (2020). "1. Soft tissue tumours: Angiolipoma". Soft Tissue and Bone Tumours: WHO Classification of Tumours. Vol. 3 (5th ed.). Lyon (France): International Agency for Research on Cancer. pp. 23–24. ISBN 978-92-832-4503-2.
  2. ↑ James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders. ISBN 0-7216-2921-0.
  3. ↑ Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. p. 1838. ISBN 1-4160-2999-0.
  4. ↑ Vijay Shankar. "Soft tissue - Adipose tissue tumors - Lipoma and variants - Angiolipoma". Pathology Outlines. Archived from the original on 2020-10-24. Retrieved 2021-01-07. Topic Completed: 1 August 2012. Minor changes: 20 March 2019
Classification
This article is issued from Offline. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.