Concizumab

Concizumab
Clinical data
Trade namesAlhemo
Routes of
administration
Subcutaneous
Drug classAntihemorrhagic
ATC code
  • None
Legal status
Legal status
Identifiers
CAS Number
DrugBank
UNII
Chemical and physical data
FormulaC6462H10004N1712O2046S46
Molar mass145887.81 g·mol−1

Concizumab, sold under the brand name Alhemo, is a monoclonal antibody used for the treatment of hemophilia B.[1] It is an anti-tissue factor pathway inhibitor.[1]

Concizumab was approved for medical use in Canada in March 2023.[3][4]

Medical uses

Concizumab is indicated for the treatment of people with hemophilia B who have factor IX inhibitors and require routine prophylaxis to prevent or reduce the frequency of bleeding episodes.[1][2]

Society and culture

Names

Concizumab is the international nonproprietary name.[5]

References

  1. 1 2 3 4 "Archived copy" (PDF). Archived (PDF) from the original on 17 April 2023. Retrieved 9 June 2023.{{cite web}}: CS1 maint: archived copy as title (link)
  2. 1 2 "Summary Basis of Decision for Alhemo". Health Canada. 31 May 2023. Retrieved 9 June 2023.
  3. 1 2 "Concizumab Product information". Health Canada. 10 March 2023. Archived from the original on 24 March 2023. Retrieved 9 June 2023.
  4. "Health Canada approves Alhemo, the first subcutaneous prophylactic treatment for people living with hemophilia B with inhibitors" (Press release). Novo Nordisk Canada. 17 April 2023. Retrieved 9 June 2023 via Newswire.
  5. World Health Organization (2013). "International nonproprietary names for pharmaceutical substances (INN): recommended INN: list 70". WHO Drug Information. 27 (3). hdl:10665/331167.


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