Aliskiren/hydrochlorothiazide
| Combination of | |
|---|---|
| Aliskiren | Renin inhibitor |
| Hydrochlorothiazide | Diuretic |
| Clinical data | |
| Trade names | Tekturna HCT, Rasilez HCT, others |
| AHFS/Drugs.com | Professional Drug Facts |
| License data | |
| Routes of administration | By mouth |
| ATC code | |
| Legal status | |
| Legal status | |
| Identifiers | |
| KEGG | |
Aliskiren/hydrochlorothiazide, sold under the brand name Tekturna HCT among others, is a fixed-dose combination medication for the treatment of hypertension (high blood pressure).[1][2] It contains aliskiren, a renin inhibitor, and hydrochlorothiazide, a diuretic.[1][2] It is taken by mouth.[1]
The most common side effect is diarrhea.[2]
Aliskiren/hydrochlorothiazide was approved for medical use in the United States in January 2008,[3] and for use in the European Union in January 2009.[2]
Medical uses
Aliskiren/hydrochlorothiazide is indicated for the treatment of essential hypertension in adults.[2]
References
- 1 2 3 4 "Tekturna HCT- aliskiren hemifumarate and hydrochlorothiazide tablet, film coated". DailyMed. 7 January 2020. Retrieved 26 August 2020.
- 1 2 3 4 5 6 "Rasilez HCT EPAR". European Medicines Agency. Retrieved 27 August 2020. Text was copied from this source which is copyright European Medicines Agency. Reproduction is authorized provided the source is acknowledged.
- ↑ "Drug Approval Package: Tekturna HCT (aliskiren/hydrochlorothiazide) NDA #022107". U.S. Food and Drug Administration (FDA). 24 December 1999. Retrieved 27 August 2020.
- Lay summary in: "Center for Drug Evaluation and Research: Application Number: 22-107: Summary review" (PDF). U.S. Food and Drug Administration (FDA).
External links
- "Aliskiren hemifumarate mixture with hydrochlorothiazide". Drug Information Portal. U.S. National Library of Medicine.
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