Etonitazepyne

Etonitazepyne
Identifiers
IUPAC name
  • 5-nitro-2-(4-ethoxybenzyl)-1-[2-(pyrrolidin-1-yl)ethyl]-1H-benzimidazole
PubChem CID
ChemSpider
UNII
Chemical and physical data
FormulaC22H26N4O3
Molar mass394.475 g·mol−1
3D model (JSmol)
SMILES
  • [O-][N+](=O)c1cc2nc(Cc3ccc(OCC)cc3)n(CCN3CCCC3)c2cc1
InChI
  • InChI=1S/C22H26N4O3/c1-2-29-19-8-5-17(6-9-19)15-22-23-20-16-18(26(27)28)7-10-21(20)25(22)14-13-24-11-3-4-12-24/h5-10,16H,2-4,11-15H2,1H3
  • Key:LQZWZCJCEPUKCJ-UHFFFAOYSA-N

Etonitazepyne (N-Pyrrolidino Etonitazene) is a benzimidazole derivative with potent opioid effects which has been sold over the internet as a designer drug and linked to numerous cases of overdose.[1][2][3]

See also

References

  1. ↑ Blanckaert P, Balcaen M, Vanhee C, Risseeuw M, Canfyn M, Desmedt B, Van Calenbergh S, Deconinck E (June 2021). "Analytical characterization of "etonitazepyne," a new pyrrolidinyl-containing 2-benzylbenzimidazole opioid sold online". Drug Testing and Analysis. doi:10.1002/dta.3113. PMID 34145779.
  2. ↑ Krotulski AJ, Papsun DM, Walton SE, Logan BK (2021). "New High Potency Synthetic Opioid N-Pyrrolidino Etonitazene (Etonitazepyne) Linked to Overdoses Across United States" (PDF). {{cite journal}}: Cite journal requires |journal= (help)
  3. ↑ Montanari, Eva; Madeo, Graziella; Pichini, Simona; Busardò, Francesco Paolo; Carlier, Jeremy (February 9, 2022). "Acute intoxications and fatalities associated with benzimidazole opioid (nitazene analog) use: A systematic review". Therapeutic Drug Monitoring. doi:10.1097/FTD.0000000000000970.



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