List of soft tissue tumors
The fifth edition (2020) WHO classification of soft tissue tumors categorizes soft tissue tumors by its histology.[1] Some new types have been introduced, based on their distinct biological behaviour, location, genetics and appearance.[2][3][4]
| Family (class) | Type | Image |
|---|---|---|
| Adipocytic tumor[5] | Lipoma |  |
| Lipomatosis |  | |
| Lipomatosis of nerve | ||
| Lipoblastoma and lipoblastomatosis | ||
| Angiolipoma |  | |
| Myolipoma of soft tissue | ||
| Chondroid lipoma | ||
| Spindle cell lipoma and pleomorphic lipoma | ||
| Hibernoma | ||
| Atypical spindle cell / pleomorphic lipomatous tumour | ||
| Atypical lipomatous tumour / well-differentiated liposarcoma | ||
| Dedifferentiated liposarcoma | ||
| Myxoid liposarcoma | ||
| Pleomorphic liposarcoma | ||
| Myxoid pleomorphic liposarcoma | ||
| Fibroblastic and myofibroblastic tumors | Nodular fasciitis |  |
| Proliferative fasciitis and proliferative myositis | ||
| Myositis ossificans and fibro-osseous pseudotumour of digits |  | |
| Ischemic fasciitis | ||
| Elastofibroma | ||
| Fibrous hamartoma of infancy |  | |
| Fibromatosis colli | ||
| Juvenile hyaline fibromatosis | ||
| Inclusion body fibromatosis | ||
| Fibroma of tendon sheath | ||
| Desmoplastic fibroblastoma Myofibroblastoma | ||
| Calcifying aponeurotic fibroma | ||
| EWSR1-SMAD3-positive fibroblastic tumour (emerging) | ||
| Angiomyofibroblastoma | ||
| Cellular angiofibroma | ||
| Angiofibroma of soft tissue | ||
| Nuchal-type fibroma | ||
| Acral fibromyxoma Gardner fibroma | ||
| Palmar fibromatosis and plantar fibromatosis | ||
| Desmoid fibromatosis | ||
| Lipofibromatosis 96 Giant cell fibroblastoma | ||
| Dermatofibrosarcoma protuberans | ||
| Solitary fibrous tumour | ||
| Inflammatory myofibroblastic tumour | ||
| Low-grade myofibroblastic sarcoma | ||
| Superficial CD34-positive fibroblastic tumour | ||
| Myxoinflammatory fibroblastic sarcoma | ||
| Fibrosarcoma; Infantile fibrosarcoma, adult fibrosarcoma | ||
| Myxofibrosarcoma | ||
| Low-grade fibromyxoid sarcoma | ||
| Sclerosing epithelioid fibrosarcoma | ||
| So-called fibrohistiocytic tumors | Tenosynovial giant cell tumor | |
| Deep fibrous histiocytoma | ||
| Plexiform fibrohistiocytic tumor | ||
| Giant cell tumor of soft tissue | ||
| Vascular tumors | Haemangiomas (Synovial haemangioma, Intramuscular angioma, Arteriovenous malformation/haemangioma, Venous haemangioma) |  |
| Anastomosing haemangioma | ||
| Epithelioid haemangioma | .jpg.webp) | |
| Lymphangioma and lymphangiomatosis | ||
| Tufted angioma and kaposiform haemangioendothelioma | ||
| Retiform haemangioendothelioma | ||
| Papillary intralymphatic angioendothelioma | ||
| Composite haemangioendothelioma | ||
| Kaposi sarcoma |  | |
| Pseudomyogenic haemangioendothelioma | ||
| Epithelioid haemangioendothelioma | ||
| Angiosarcoma | ||
| Pericytic (perivascular) tumours | Glomus tumour | |
| Myopericytoma, including myofibroma | ||
| Angioleiomyoma | ||
| Smooth muscle tumors | Leiomyoma | |
| Leiomyosarcoma | ||
| EBV-associated smooth muscle tumour[4] | ||
| Inflammatory leiomyosarcoma | ||
| Skeletal muscle tumours | Rhabdomyoma | |
| Embryonal rhabdomyosarcoma | ||
| Alveolar rhabdomyosarcoma | ||
| Pleomorphic rhabdomyosarcoma | ||
| Spindle cell / sclerosing rhabdomyosarcoma | ||
| Ectomesenchymoma | ||
| Gastrointestinal stromal tumour | ||
| Chondro-osseous tumours | Soft tissue chondroma
Extraskeletal osteosarcoma |
|
| Peripheral nerve sheath tumours | Schwannoma
Perineurioma Dermal nerve sheath myxoma Solitary circumscribed neuroma Ectopic meningioma and meningothelial hamartoma Benign triton tumour / neuromuscular choristoma Hybrid nerve sheath tumour Malignant peripheral nerve sheath tumour Malignant melanotic nerve sheath tumour |
|
| Tumours of uncertain differentiation | ||
| Intramuscular myxoma | ||
| Juxta-articular myxoma | ||
| Deep (aggressive) angiomyxoma | ||
| Atypical fibroxanthoma | .jpg.webp) | |
| Angiomatoid fibrous histiocytoma | ||
| Ossifying fibromyxoid tumour | ||
| Myoepithelioma, myoepithelial carcinoma, and mixed tumour | ||
| Pleomorphic hyalinizing angiectatic tumour of soft parts | ||
| Haemosiderotic fibrolipomatous tumour | ||
| Phosphaturic mesenchymal tumour | ||
| NTRK-rearranged spindle cell neoplasm (emerging) | ||
| Synovial sarcoma | ||
| Epithelioid sarcoma | ||
| Alveolar soft part sarcoma | ||
| Clear cell sarcoma of soft tissue | ||
| Extraskeletal myxoid chondrosarcoma | ||
| Desmoplastic small round cell tumour |  | |
| Extrarenal rhabdoid tumour | ||
| PEComa | ||
| Intimal sarcoma | ||
| Undifferentiated sarcoma | ||
References
- ↑ Bansal, Abhinav; Goyal, Surbhi; Goyal, Ankur; Jana, Manisha (October 2021). "WHO classification of soft tissue tumours 2020: An update and simplified approach for radiologists". European Journal of Radiology. 143: 109937. doi:10.1016/j.ejrad.2021.109937. ISSN 1872-7727. PMID 34547634. Archived from the original on 2022-07-01. Retrieved 2022-06-20.
- ↑ WHO Classification of Tumours Editorial Board, ed. (2020). "1. Soft tissue tumors". Soft Tissue and Bone Tumours: WHO Classification of Tumours. Vol. 3 (5th ed.). Lyon (France): International Agency for Research on Cancer. pp. 1–320. ISBN 978-92-832-4503-2.
- ↑ Houdek, Matthew T. (2023). "1. Approach to bone and soft tissue tumors". In Folpe, Andrew L.; Nielsen, Gunnlaugur Petur (eds.). Bone and Soft Tissue Pathology: A Volume in the Foundations in Diagnostic Pathology Series (2nd ed.). Philadelphia: Elsevier. ISBN 978-0-323-75871-0. Archived from the original on 2023-02-26. Retrieved 2023-06-13.
- 1 2 Nobori, Alexander K.; Dry, Sarah M. (2023). "6. Smooth muscle tumors". In Folpe, Andrew L.; Nielsen, Gunnlaugur Petur (eds.). Bone and Soft Tissue Pathology: A Volume in the Foundations in Diagnostic Pathology Series (2nd ed.). Philadelphia: Elsevier. pp. 161–174. ISBN 978-0-323-75871-0. Archived from the original on 2023-07-09. Retrieved 2023-07-08.
- ↑ Thway, Khin (January 2022). "What's new in adipocytic neoplasia?". Histopathology. 80 (1): 76–97. doi:10.1111/his.14548. ISSN 1365-2559. PMID 34958506. Archived from the original on 2023-02-25. Retrieved 2022-06-20.
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